2013, Número 4
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Rev Cubana Plant Med 2013; 18 (4)
Determinación in vitro de la capacidad antioxidante de extractos y compuestos fenólicos de hojas de Ugni molinae Turcz
Avello LM, Pastene NE, González RM, Bittner BM, Becerra AJ
Idioma: Ingles.
Referencias bibliográficas: 40
Paginas: 596-608
Archivo PDF: 293.36 Kb.
RESUMEN
Introducción: Ugni molinae Turcz. (
Myrtaceae) es una planta que se distribuye en el centro-sur de Chile, incluido el archipiélago de Juan Fernández. Las hojas se han utilizado en medicina popular para diarreas e infecciones bucales, por sus propiedades astringentes y antisépticas.
Objetivo: la actividad antioxidante de los dos extractos (acetato de etilo y metanólicol) de las hojas de
Ugni molinae se evaluó mediante diferentes ensayos.
Métodos: HPLC (
high performance liquid chromatography) para el análisis químico y los métodos antioxidantes
in vitro.
Resultados: los perfiles HPLC de ambos extractos mostraron la presencia de flavan-3-oles (catequinas) y ácido gálico, flavonoides y derivados del ácido cafeico como constituyentes principales. Estos extractos mostraron actividad significativa frente a 2,2-difenil-1-picrilhidrazilo (DPPH), capacidad reductora del ión cobre (CUPRAC) y ensayos frente al radical hidroxilo. Es importante destacar que el blanqueamiento de liposomas de b-caroteno-linoleato y la oxidación producida por cobre de LDL (
low density lipoprotein) humana fueron evitados por ambos extractos.
Conclusiones: los resultados sugieren que los extractos de
Ugni molinae ricos en polifenoles podrían evitar la peroxidación lipídica y el daño de radicales libres.
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