2015, Número 2
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Alerg Asma Inmunol Pediatr 2015; 24 (2)
Churg-Strauss: presentación de un caso
Azamar JAA, García DM, Rodríguez GM, Mendoza HDA, Escamilla QC
Idioma: Español
Referencias bibliográficas: 32
Paginas: 68-72
Archivo PDF: 262.88 Kb.
RESUMEN
El síndrome de Churg-Strauss, también conocido como poliangeitis granulomatosa alérgica, es una vasculitis de pequeños vasos que afecta pulmón, nervios periféricos, piel y, de manera menos frecuente, corazón y tubo digestivo. Su etiología es todavía desconocida y el diagnóstico difícil debido a la variabilidad en su cuadro clínico. Clínicamente se caracteriza por la presencia de asma, rinitis alérgica y eosinofilia, y a nivel microscópico por una tríada típica que incluye vasculitis necrotizante, presencia de granulomas y eosinofilia extravascular. Fue descrita por primera vez por Churg y Strauss en 1951; sin embargo, se trata de una enfermedad rara y de presentación en la edad adulta, por lo que se sabe poco de sus características clínicas en niños. Lanham et al, en 1984, sugirieron una serie de criterios para su diagnóstico; y posteriormente, el Colegio Americano de Reumatología propone seis criterios para su clasificación. Se sabe poco acerca del tratamiento óptimo en población pediátrica; empero, un diagnóstico oportuno mejora significativamente el pronóstico. Presentamos el caso de un paciente femenino de 13 años de edad con asma de difícil control en quien se integra el diagnóstico de síndrome de Churg-Strauss.
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