2012, Number 3
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Rev Mex Med Repro 2012; 4.5 (3)
Assisted hatching in patients over 34 years. Experience Centro Médico Nacional 20 de Noviembre, ISSSTE
Moreno GJD, González BJE, Regalado HMÁ
Language: Spanish
References: 29
Page: 116-119
PDF size: 88.13 Kb.
ABSTRACT
Objective: To determine the pregnancy rate with assisted biochemical hatching in patients older than age 34 years.
Patients and method: Case report. Human Reproduction Service of the Centro Médico Nacional 20 de Noviembre, ISSSTE. Patients older than 34 years who agreed to assisted hatching with acidic Tyrode’s solution. Assisted hatching with acidic Tyrode’s solution to embryos on their 3
rd day of development.
Results: We included 34 patients aged 38.6 ± 4.7 years, follicle stimulating hormone to initiate the cycle of stimulation of 9.2 ± 5 IU/L, antral follicles 6.7 ± 5.1. Embryo transfer was performed on 34 patients, presenting a pregnancy rate of 32.4% (11 of 34 patients).
Conclusions: The study showed a pregnancy rate of 32.4%. It requires a randomized controlled trial to determine efficacy of this technique.
REFERENCES
Cohen J. Assisted hatching of human embryos. J In Vitro Fert Embryo Transf 1991;8:179-190.
Balaban B, Urman B, Alatas C, Mercan R, Muncu A, Isiklar A. A comparison of four different techniques of assisted hatching. Human Reprod 2002;17:1239-1243.
Bider D, Livshits A, Yonish M, Yemini Z, et al. Assisted hatching by zona drilling of human embryos in women of advanced age. Hum Reprod 1997;12:1239-1243.
Liu HC, Cohen J, Alikani M, Noyes N, Rosenvaks Z. Assisted hatching facilities earlier implantation. Fertil Steril 1993;60:871-875
Osagi E, Hooper L, Seif M. The impact of assisted hatching on live birth rates and outcomes of assisted conception: a systematic review. Human Reprod 2003;18:1828-1835.
Magli MC, Gianaroli L, Ferraretti AP, Fortini D, et al. Rescae of implantation potential in embryos with poor prognosis by assisted zona hatching. Hum Reprod 1998;13:1331-1335.
Joris H, De Vos A, Janssens R, Devroey P, et al. Comparison of the results of human embryo biopsy and outcome of PGD after drilling using acid Tyrode medium or laser. Hum Reprod Biomed Online 2002;4:27-31.
Das S, Blake D, Farquhar C, Seif MMW. Assisted hatching on assisted conception (IVF and ICSI). Cochrane Database Syst Rev 2009(2): CD 001894.
Gabrielsen A, Bhatnager PR, Petersen K, Linderberg S. Influence of zona pellucida thickness of human embryos on clinical pregnancy outcome following in vitro fertilization treatment. J Assist Reprod Genet 2000;17:323-328.
Huai LF. A retrospective study comparing three different assisted hatching techniques. Fertility and Sterility 2009; 91:1323-1325.
Yao-Yuan H, Chun-chia H, Tzu-Chun C, et al. Laser-assisted hatching of embryos is better than the chemical method for enhancing the pregnancy rate in women with advanced age. Fertility and Sterility 2002;78:179-182.
Magli MC, Gianaroli L, Ferraretti AP, et al. Rescae of implantation potential in embryos with poor prognosis by assisted zona hatching. Human Reprod 1998;13:1331-1335.
Tzong-Chyi S, Su-Ru C, Heng-Kien A, et al. Herniated blastomer following chemically assisted hatching may result in monozygotic twins. Fertility and Sterility 2001;75:442-444.
Sunny H, Amin A. Assisted hatching is associated with a higher ectopic pregnancy rate. Fertility and Sterility 2004;81:1701-1703.
Cohen J. Assisted hatching of human embryos. J In Vitro Fert Embryo Transf 1991;8:179-190.
Balaban B, Urman B, Alatas C, Mercan R, Muncu A, Isiklar A. A comparison of four different techniques of assisted hatching. Human Reprod 2002;17:1239-1243.
Bider D, Livshits A, Yonish M, Yemini Z, et al. Assisted hatching by zona drilling of human embryos in women of advanced age. Hum Reprod 1997;12:1239-1243.
Liu HC, Cohen J, Alikani M, Noyes N, Rosenvaks Z. Assisted hatching facilities earlier implantation. Fertil Steril 1993;60:871-875
Osagi E, Hooper L, Seif M. The impact of assisted hatching on live birth rates and outcomes of assisted conception: a systematic review. Human Reprod 2003;18:1828-1835.
Magli MC, Gianaroli L, Ferraretti AP, Fortini D, et al. Rescae of implantation potential in embryos with poor prognosis by assisted zona hatching. Hum Reprod 1998;13:1331-1335.
Joris H, De Vos A, Janssens R, Devroey P, et al. Comparison of the results of human embryo biopsy and outcome of PGD after drilling using acid Tyrode medium or laser. Hum Reprod Biomed Online 2002;4:27-31.
Das S, Blake D, Farquhar C, Seif MMW. Assisted hatching on assisted conception (IVF and ICSI). Cochrane Database Syst Rev 2009(2): CD 001894.
Gabrielsen A, Bhatnager PR, Petersen K, Linderberg S. Influence of zona pellucida thickness of human embryos on clinical pregnancy outcome following in vitro fertilization treatment. J Assist Reprod Genet 2000;17:323-328.
Huai LF. A retrospective study comparing three different assisted hatching
techniques. Fertility and Sterility 2009; 91:1323-1325.
Yao-Yuan H, Chun-chia H, Tzu-Chun C, et al. Laser-assisted hatching of embryos is better than the chemical method for enhancing the pregnancy rate in women with advanced age. Fertility and Sterility 2002;78:179-182.
Magli MC, Gianaroli L, Ferraretti AP, et al. Rescae of implantation potential in embryos with poor prognosis by assisted zona hatching. Human Reprod 1998;13:1331-1335.
Tzong-Chyi S, Su-Ru C, Heng-Kien A, et al. Herniated blastomer following chemically assisted hatching may result in monozygotic twins. Fertility and Sterility 2001;75:442-444.
Sunny H, Amin A. Assisted hatching is associated with a higher ectopic pregnancy rate. Fertility and Sterility 2004;81:1701-1703.